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YARUMAL, - AUGUST 18 - Alirio sits in his living room with his son Alexis, 6, snuggles in and his wife Marta. Alirio, 42, is a coffee farmer who is also a participant in the University of Antioquia study who lives near Yarumal. The study, lead by Dr. Francisco Lopera, a behavioural neurologist at Medellin's University of Antioquia, researches a local family tree with a genetic mutation that causes early-onset Alzheimer's disease. The Colombian family's genetic curse may be the world's best hope for an Alzheimer's cure. In that family tree researchers have the perfect group to study the disease and have now begin a clinical trial to see if they have a medication that might be able to delay onset. in Medellin. (Steve Russell/Toronto Star via Getty Images)

A moving story reveals hidden human cost of drug trials

2 April 2025

Drug trials are vital to medicine, but what of those taking part? Jennie Erin Smith's moving new book about what happened in a rural community hit by early-onset Alzheimer's disease gives them a voice

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