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Health

GLP-1 drugs are only the start – the powerful drugs to expect next

The race is under way to make faster, cheaper and better GLP-1 drugs that will go beyond reducing obesity levels to treating some of our most difficult conditions

By Michael Le Page

26 March 2025

·ï»Ë²ÊƱ. Science news and long reads from expert journalists, covering developments in science, technology, health and the environment on the website and the magazine.

Jon Krause

Obesity rates have been increasing in the US for decades, but in 2023 they fell – at least in part because of the burgeoning popularity of the “miracle drug” semaglutide. Approved for treating obesity only in 2021, it is in short supply and is very expensive, but it has already had an extraordinary impact (“How semaglutide and similar drugs work”, below).

Yet this could just be start. With many companies racing to market rival versions of semaglutide in cheaper and easier-to-take forms, as well as mounting evidence that that GLP-1 drugs can target a host of health conditions, the treatments…

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