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Health

We are finally beginning to understand migraines and how to treat them

After 40 years of research, scientists have uncovered what happens in the brain during a migraine and developed promising new drugs to tackle the condition. Here’s what we now know – and what still remains unanswered

By Jessica Hamzelou

26 January 2022

·ï»Ë²ÊƱ. Science news and long reads from expert journalists, covering developments in science, technology, health and the environment on the website and the magazine.

Jasu Hu

I WAS 15 years old and halfway through a family meal when the blow to my head came out of nowhere. It felt as if someone had clobbered me on the side of the skull with a mallet, the sudden pain making me drop my fork. Then came a second hit. And a third. I remember pleading with my sister to stop her noisy whingeing before running to hide under a duvet until the pain eventually subsided. I had experienced my first migraine.

Twenty years later, my migraine-coping technique remains largely unchanged, except that it is now my toddler whose…

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